SUMMARY
WU, T.H.
Clinical and scintillographic modifications in chronic ischemic
stroke patients treated with subcutaneous electrical stimulation.
São Paulo, 2001. 111p. Tese (Doutorado) - Faculdade de Medicina,
Universidade de São Paulo.
The majority of individuals who survive a stroke are disabled because
of a persistent neurological impairment. Further improvement is not
usually seen after 18 months of conventional treatments. The objective
of this study is to evaluate the efficacy of subcutaneous electrical
stimulation of the scalp on the functional recovery of patients more
than 18 months post ischemic stroke. Using cerebral perfusion scintillography,
changes in cold areas were associated with clinical, neurological
and functional findings. A total of sixty-two male and female patients
from 24 to 65 years old were prospectively randomized into two groups
for this double blind clinical trial. In one group, thirty-four patients
received ten sessions of low frequency electrical stimulation (2/100
Hz) applied through subcutaneous scalp needles at the projections
of the motor, sensory, frontal and temporal associative areas of the
Penfield homunculus for 30 minutes twice a week. In the other group,
twenty-eight patients received placebo electrical stimulation twice
a week for ten sessions applied through disconnected electrical cables
on the scalp. They received seven seconds of stimulation for each
of the functional brain areas represented at the scalp, namely: sensory
and motor areas of the face, lower and upper limbs, as well as the
supplementary motor area. Patients were evaluated prior to and immediately
after the ten treatment sessions by blind examiners. Barthel and Rankin
scales were used for the functional evaluation, and the National Institutes
of Health Stroke Scale was used for the neurological rating. Subcutaneous
scalp electrical stimulation showed statistically significant neurological
improvement, but did not modify the quantitative functional and scintillographic
patterns in chronic ischemic stroke patients.
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